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Administrative Information: Table 2.1 Patient Accrual Study sample size Total patients entered Average monthly accrual for the study 1540 1579 31.2.
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Skin conditions are of great imporwidespread and very itchy. The tance in the diagnosis of rash is often the first outward sign HIV AIDS. Skin is often the first of HIV infection, and occurs as barrier the human body has early as two years before the against disease causing organother signs of AIDS develop. In isms. Skin is also an external indiUganda it occurs in 35 per cent of cator of disease. The health worker AIDS cases reported. No organism may use skin conditions to predict has yet been identified as the progression of immunodeficiency cause of this rash. in a patient with HIV infection. The small flat spots macules ; The WHO clinical criteria for develop into papules or small blisAIDS diagnosis in Africa include ters. Scratching may lead to secfour skin conditions: Kaposi's sarondary bacterial infection. Similar coma, Herpes zoster, Herpes simrashes may occur with syphilis plex and pruritic itching ; although syphilis is classically nonmaculopapular rash. These have itchy ; , drug reaction and scabies. been reported to have a predictive value for HIV seropositivity rangTreatment: There is no specific ing from 71 per cent to 98 per treatment for prurigo. The patient cent. However, it is important to can be reassured that the itching remember that many skin condilasts only a short time but a pertions suffered by people with HIV manent hyperpigmented 'rash' infection are also seen in nonmay remain. During the itchy infected patients. In HIV infected patients and noninfected patients, skin conditions may arise from single or multiplecauses. For simplicity they may be classified as follows.
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